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Baclofen given orally increased the incidence of fetal structural abnormalitiesomphalocelesin ratsReductions in food intake and body weight gain were observed in the damsFetal structural abnormalities were not observed in mice or rabbits.

Lioresal is not indicated in the treatment of skeletal muscle spasm resulting from rheumatic disorders.

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In patients with epilepsythe clinical state and electroencephalogram should be monitored at regular intervalssince deterioration in seizure control and EEG have been reported occasionally in patients taking Lioresal.

Drug interactions may change how your medications work or increase your risk for serious side effectsThis document does not contain all possible drug interactionsKeep a list of all the products you useincluding prescription/nonprescription drugs and herbal productsand share it with your doctor and pharmacistDo not startstopor change the dosage of any medicines without your doctor’s approval.

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